Not-So-Technical Stuff
spamcop.net - FREE as of Nov. 21, 2010
SpamCop parses reported email, sending warning information to the internet service provider responsible for hosting the services used by the spammer (web sites and email sending sites). SpamCop also uses the information to generate SpamCop's free blocking list.
Adcomplain - FREE as of Nov. 21, 2010
Automatically analyzes the message, composes an abuse report, and mails the report to the offender's internet service provider. The report is displayed for your approval prior to mailing. Adcomplain can be invoked from the command line or automatically from many news and mail readers.
Unix, Windows 95/NT
SpamKiller - NOT FREE $39.95 as of Nov. 21, 2010
SpamKiller handles any number of e-mail accounts, and supports both POP3 and MAPI type accounts. SpamKiller can play sounds and run programs automatically when you receive new e-mail. Different events are triggered depending on the type of the incoming messages (i.e. New mail, New possible spam, Killed spam and Mail from a friend.). Each account has its own set of configurable events. You can create new filters and/or use the preset filters, and filter on any part of the message. SpamKiller can send both automatic and manual complaints.
POP3 and MAPI accounts